Neonatal lupus erythematosus is not always benign
نویسندگان
چکیده
منابع مشابه
Neonatal Lupus Erythematosus
Neonatal lupus erythematosus (NLE) refers to a clinical spectrum of cutaneous, cardiac, and systemic abnormalities observed in newborn infants whose mothers have autoantibodies against Ro/SSA and La/SSB. The condition is rare and usually benign and self-limited but sometimes may be associated with serious sequelae. We review the pathophysiology, clinical features, and management of infants with...
متن کاملNeonatal Lupus Erythematosus (NLE)
Neonatal lupus erythematosus (NLE) or neonatal lupus syndrome (NLS) is a rare syndrome seen in 1-2% of neonates with auto-antibodies to SSA/Ro, SSB/La and or U1 RNP, passively transferred transplacentally from the mother who is either asymptomatic or having manifestations of Sjogren’s syndrome, SLE or other systemic rheumatic disease, characterized by cutaneous, cardiac or rarely both clinical ...
متن کاملNeonatal lupus erythematosus.
We describe case report of a 45 days old male baby with neonatal lupus erythematosus, who presented with 3rd degree congenital heart block and depigmented skin lesions on face and upper part of body. Diagnosis of the baby was confirmed by anti nuclear levels and skin biopsy.
متن کاملNeonatal lupus erythematosus.
Neonatal lupus erythematosus is an immune-mediated disease that rarely is associated with congenital heart block. Transient hepatitis, thrombocytopenia and anemia can also occur. We describe a case of neonatal lupus erythematosus and review the clinical and laboratory manifestations of this rare disease. Its only clinical sign might be an annular facial rash. The rash is usually diagnostic, but...
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In lupus erythematosus, elevated serum creatinine levels and urinary abnormalities implicate a kidney disorder, which may not always be lupus nephritis as defined by the current classification of the International Society of Nephrology/Renal Pathology Society. The signs of renal dysfunction may be caused by lupusunrelated renal injury such as drug toxicity or infection or by lupus-associated me...
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ژورنال
عنوان ژورنال: BMJ
سال: 2006
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.332.7544.796